What is insulin resistance? A lot of
people have heard of insulin resistance they know that it’s a big problem
but how big a problem is it and where does it come from is insulin a bad thing?
well today we’re going to talk about all these things so that you understand it
and hopefully so that you understand it well enough to help others start
understanding it because this is maybe the biggest health problem that we have
in the Western world stay tuned (logo) insulin resistance is exactly what it sounds like it’s the body’s resistance to insulin insulin is a good
thing it’s been around for as long as life has been around and it helps us
survive the purpose of insulin is to store the excess whenever we have feast
versus famine when there’s a feast and we have some extra then the insulin is
there to store it so insulin is an anabolic hormone anabolic means to build
up and what are we building up we’re building up tissues we’re building up
reserves we’re building muscles we’re building fat we’re building up anything
that can help us survive later so when we have plenty we want to save for a
rainy day so that later when we don’t have so much we can start using those
stores we can break down the stores and that’s called catabolic but today we’re
going to talk about the anabolic part because that’s what insulin is. the purpose of everything that you eat is to turn that food into fuel and building blocks and
insulin has to do with both but when we talk about insulin resistance we’re
primarily concerned about the fuel apart so anytime that you eat something that
raises blood sugar that sugar is in the bloodstream and it can’t get into the
cell without the help of insulin so insulin is like a key it’s a hormone
that plugs into the lock and it opens up the door so
the glucose can get inside the cell and this is a very tightly very precisely
regulated process it doesn’t happen by itself and remember that insulin is an
anabolic hormone it stores the excess so when we eat carbohydrates then there is
an enormous response of insulin because that purpose of that carbohydrate is
part of it is fuel in the moment but most of it gets converted into fat that
we can put in storage and use for later protein also has a moderate insulin
response because protein also gets turned into tissues we use it to build
tissues and muscles but fat doesn’t have any insulin response to speak of it’s
virtually zero because fat doesn’t get turned into storage or into tissue it is
already the form that the body needs it which is fuel so when we eat carbs we
want to turn it into fat for future use but the fat itself is already fuel so
it doesn’t have an insulin response to it everything that you eat is to become
blood sugar one way or another and the body likes it to be in a very very
narrow range and if you eat after a meal it should be somewhere between 80 to 120
if it’s been awhile since you ate then it should be somewhere probably between
75 and 95 a fasting blood glucose and that’s a very very narrow band that
means that at any given time you have it about one teaspoon of sugar in your
bloodstream so anything more than that is excess and it has to be stored and
that’s what the insulin does and why does the body want the blood glucose so
tightly regulated because excess is toxic to the brain and diabetic without
insulin where the blood sugar go through the roof they can end up in a
coma or if they take too much insulin so their blood sugar plummets they can also
end up in a coma so on the one hand it’s toxic on the other hand it is too low to
where the body the brain doesn’t have enough fuel to function that’s why the
brain functions the best it can do the things it needs to do at a very steady
supply it’s like you throw a log on the fire and it gives a steady stream of
warmth for for many many hours carbohydrates is more like you throw a
can of gasoline on the fire and it all burns up in an instant so if we want to
capture that all that energy then we have to be able to convert it to
something else and store it so that’s what’s happening so let’s look at a
normal situation with a cell so this here is a cell and inside it I’ve
written little triangles that are supposed to be glucose that’s not their
normal shape but it’s just easier to draw that way and we have a small number
then some of that glucose gets converted into fat and some of the fat is
circulating around on its own but in both cases we have just enough for that
cell to function for a while and then outside the cell we have more glucose
that’s the blood glucose it hasn’t entered the cell yet and the red circles
are insulin and the insulin is there to assist the glucose to enter the cell so
as we use up some glucose inside the cell then it needs to be replenished so
that the cell has fuel for its continued function and this would be a normal
situation it’s tightly regulated it’s a flow and it’s an ongoing process that
gives the body what it needs and not too much not too little but when we start
eating a lot of carbohydrates and we start eating many many times a day and
we start eating snacks in between now we have more carbohydrate we have
more glucose so that’s all of these little triangles in the cell is jam-packed with glucose and when the cell can’t use that glucose it
starts converting it into fat and it starts storing inside the cell first as
fat and then it starts spilling over so that it gets into the blood and then it
can get into other cells to be stored as fat anything the body can’t use at the
time has to be stored and then outside the cell we still have tons and tons of
glucose there’s an abundance there’s an excess of glucose outside the cell
because we keep eating carbohydrates we keep eating frequent meals so the body
doesn’t have a chance to burn through the stuff that you ate at the previous
meal or yesterday so the stuff just keeps building up but remember in the
bloodstream it’s toxic the brain can’t handle that much glucose so that’s an
emergency and the body says hey we got to get this glucose out of the
bloodstream let’s make a bunch of insulin so the more glucose we have the
more insulin is needed to push to open up the door for that glucose to get into
the cell but the cell is already full where is it going to go and this is
where the cell becomes insulin resistant because there is a excess of glucose
inside the cell there’s an excess of glucose outside the cell because of the
excess glucose outside there’s also an abundance of insulin called
hyperinsulinemia there’s too much insulin and all that insulin is trying
to push the glucose in but there is no room and the cell is saying can’t take
anymore I don’t care how desperate you are to get rid of that
glucose in the bloodstream we have all we can handle
that is how insulin resistance happens and the problem now is because the
insulin is a storage hormone it’s an anabolic hormone it works primarily to
put things inside the cell rather than allowing them out then we have all of
this fat inside this cell and an inside a bunch of other fat cells and inside
the liver but we can’t get to it because there’s too much insulin insulin is a
storage hormone it’s a one-way hormone it puts things in it doesn’t allow
things to get back out so if we look at the top reasons of why this mechanism
happens then it has to do with one blood glucose when we eat a lot of
carbohydrates then we’re driving up glucose on a regular basis but that is
typically not enough because there are lots of cultures around the world that
have subsisted on a high carb diet they’ve eaten potatoes they’ve eaten
corn they’ve eaten rice at very very high levels but they still don’t develop
insulin resistance or at least not significantly or at least not in young ages so the second thing that’s required is frequency and if you just
eat a couple times a day you could probably live a long life and eat high
carb and not develop insulin resistance the third factor though is the key and
this is where our societies have changed so much and so quickly and the third
reason is sugar because sugar is a special thing sugar exists in nature in
very very limited quantities its present in vegetables its present in milk its
present in fruits but in small quantities but when we refine it when we
start adding it when we extract it a white crystal stuff and put it in a bag
and we add it to catch up and to dressings and to cookies and ice cream
now we’re getting many many many times more than we ever could
from nature and what’s the problem with that the problem with sugar is that it
is 50% glucose and 50% fructose and the fructose is a special kind of sugar the
glucose can go straight into the bloodstream and it can be dispersed and
every cell in the body can use the glucose so if you’re weighing 200 pounds
then you have 200 pounds of cells that can use glucose so that glucose gets
evenly dispersed and it gets burned off by those cells but the fructose can only
be metabolized by the liver so now the sugar is 50% glucose and 50% fructose so
if you ate a hundred grams of sugar you got 50 grams of glucose to go evenly but
you also have 50 grams of fructose that can only be metabolized and transformed
by the liver and the liver even though it’s a sizable organ it’s somewhere
around three pounds so the liver now is getting 70 times more sugar than the
rest of the body on average and that is the overload that breaks the camel’s
back and the liver is your primary metabolic organ it’s supposed to do
hundreds of different things it converts one thing to another it detoxifies you
it handles your proteins it changes blood blood sugar it detoxifies alcohol
it makes glycogen and does all these different things and now we just threw a
70 times bigger load of sugar onto the liver so this the the packed cell this
is what happens to the liver and so sugar accelerates insulin resistance
many many many times it is even you could go so far as to say it’s difficult
to get insulin resistance without sugar but once you have insulin resistance
now you kind of broke the machine you have a certain carbohydrate tolerance
built into the machine but the sugar broke it and once it’s broken now you
have to backtrack you have to go much much further you have to be much much
stricter to reverse it then you would have to be to maintain it and then in
the light 1900s I don’t know the exact date 70s 80s somewhere they figured that
you know sugar is conceivably the worst food ever devised by mankind but let’s
see if we can make it a little bit worse let’s see if we can really ramp it up
and create some poison on steroids if you will and that’s when they figured
out how to make high fructose corn syrup because now they developed a cheap
sweetener that has a higher rate of fructose so fructose is the stuff that
poisons the liver because they can’t go anywhere else and high fructose corn
syrup is anything that has higher than 50% fructose so they just increased the
horrendous portion of sugar even a little bit more and now we’re seeing and
then you combine that with the low fat diet and you scare people from fat and
all of a sudden we have an epidemic of epic proportion of insulin resistance
and diabetes and obesity and so forth so there are many ways of figuring out if
your insulin resistant and we’re going to talk more in later videos but one of
the basic things is to measure your a1c your a1c your hemoglobin a1c is a
three-month average it’s a way of measuring what your blood sugar is on
average over a period of three to four months and if it is below five point
three then in my opinion it’s good it’s okay you are insulin sensitive and in
the medical world if it is between five point seven and six point four then you
are pre diabetic then your insulin resistance
equals pre-diabetes and if it’s over 6.5 then you have diabetes and according to
current numbers I don’t have the exact ones but approximately 20% of the
population is diabetic and according to official number somewhere around 30
percent are insulin disease resistance or pre-diabetic what does that mean it
means if you don’t change something if you just keep doing what you’re doing
then if you’re pre-diabetic you are more than likely to become diabetic at some
point in time and the official guidelines suggests that you’re okay all
the way up to 5.7 but it kind of it’s obvious that it doesn’t start at 5.7 you
don’t just all of a sudden end up there it’s a slippery slope so I would say
that you want to start paying attention as soon as you get over 5.3 now you know
that you’re developing you’re starting the early signs so instead of waiting
for the full-blown diabetes or the severe insulin resistance why don’t we
start working at it when you have mild or slight insulin resistance and just to
give you an idea of how widespread this problem is then you could just look
around and imagine the number of overweight people which is somewhere
around three-quarters of the population in the United States and that matches
very very closely to these numbers 20% diabetic 30% insulin resistant and in my
opinion 30% and I’m guessing at the number of people that have that but just
based on overweight people and lifestyles I would say some around 80%
of the population have mild to severe insulin resistance or diabetes and again
if you don’t change something then that pre-diabetes that insulin resistance
will continue to get worse and why should you be concerned because
pre-diabetes and biddies are associated with weight gain
increased blood pressure increased risk of stroke and increased risk of
cardiovascular disease so all of the stuff that kills the most people is
associated with insulin resistance and pre-diabetes
when is the best time to stop it when it’s full-blown or in the early stages
the answer is pretty obvious so let me ask you something
based on what we’ve talked about based on your current understanding of based
on what we talked about does this have anything to do with food and if you paid
any attention I think you would say that yes it has everything to do with food
and why am I asking that because when I went to do get my own blood test done
there was a little flyer on the wall from the CDC government agency Centers
for Disease Control and they had a screening test where they wanted to
check and have a little questionnaire to see if you were insulin resistant and
here’s what they were asking have you had a baby that weighed over nine pounds
at birth then give yourself a point do you have a sibling with type-2 diabetes
give yourself a point do you have a parent with type-2 diabetes
give yourself a point are you overweight give yourself five points are you under
65 years of age but you do little to no exercise then give yourself five points
are you between 45 to 64 years old give yourself five points are you over 65
give yourself nine points and then they’re saying if you are three to eight
points then you should watch your lifestyle
you should eat low-fat food you should eat high grain food you should try to be
active don’t smoke and lose weight isn’t that great advice eat low-fat
because that has no insulin response eat high grain because that has the most
insulin response be active is a good idea because activity helps the body
burned through the glucose that’s in the muscles and the muscles can get the
glucose from the bloodstream with less insulin when you’re active so that is a
good idea and of course don’t smoke that’s not a new thing that’s good
advice and then they say lose weight and you’re screaming after understanding
this I would love to but I can’t because I’m insulin resistant alright they’re
getting everything backwards the insulin resistance insulin is a storage hormone
it’s the insulin that stored the weight and it’s the insulin that keeps you from
burning it so that’s useless advice because it’s sort of just stating the
obvious you would if you could and if you’re nine points or more which the
only thing you have to do is to be over 65 to get nine points then you should
see your doctor because you’re probably insulin resistant and they’re right
there the statistics point to that fact but what they’re missing is there’s not
a single question here about food how many sodas do you drink how much sugar
do you eat do you eat processed foods none of that all of this means is if you
had a baby over nine pounds you produced a lot of insulin because you ate a lot
of carbs if you have a sibling with type-2 diabetes they ate a lot of carbs
so probably you eat a lot of carbs if you had a parent with type-2 diabetes
they ate a lot of carbs so you probably ate a lot of carbs if you are overweight
then you probably ate a lot of carbs if you are let under 65 and you don’t
exercise then you probably ate a lot of carbs but you didn’t exercise to give
your body a chance to burn it off and by the time to develop insulin
resistance now the exercise is still beneficial but it can’t really fix the
problem if you’re 45 to 64 then that’s how long you’ve been alive eating carbs
and if you’re over 65 years old then you’ve had more than 65 years to eat
carbs this is what they’re saying but there’s no question about food in here
and then they tell you eat low fat high grain etc so based on that based on that
complete ignorance it is no mystery why we have 80 percent overweight people and
80 percent insulin resistance and why the top killers are things like
cardiovascular disease stroke and diabetes we have to start understanding
that it’s a storage problem the cells have too much fuel and in the presence
of insulin they can’t use it and what’s the medical solution is to give people
things to push even more to help the body push more sugar into the cell to be
converted to fat that’s the solution and when the body can’t keep up anymore and
when the metformin and the glucophage is aren’t enough then we inject them with
insulin to try to push even more inside and it’s the exact opposite of the
solution so that’s how insulin resistance works we’re going to do some
more videos on it so that we can expand and and provide more detail and specific
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